Genome Scale-Differential Flux Analysis reveals deregulation of lung cell metabolism on SARS-CoV-2 infection
Fig 7
(A) A pathway wise description with the flux changes of the constituent altered reactions in the pathways along with the number of such reactions affected by differential phosphorylation and protein-protein interactions with viral proteins. (B) The prospective mechanism of flux regulation by post-translational modification or allosteric effects on enzymes mediated by viral proteins. (C) The enrichment of differentially phosphorylated enzymes and enzymes interacting with viral proteins in the set of altered reactions identified by GS-DFA.