Genome Scale-Differential Flux Analysis reveals deregulation of lung cell metabolism on SARS-CoV-2 infection
Fig 6
GS-DFA reveals altered pathways in infected cells and post-translational modifications in infected cells are enriched in altered reactions.
(A) Enriched pathways (subsystems) in the SARS-CoV-2 infected NHBE cells as revealed by GS-DFA analysis. The presented reactions have flux change (as described in materials and methods) greater than 0.82 and have adjusted p-value less than 0.05 (B) Some of the pathways altered in the SARS-CoV-2 infected cells that could have therapeutic relevance (Created with BioRender.com).