Prediction of amphipathic helix—membrane interactions with Rosetta
Fig 2
Heatmaps for the Rosetta scans at the best-scoring tilt angle for six LK peptides calculated with the RosettaMembrane (A), franklin2019 (B), and ref2015_memb score functions (C). The x-axis represents the rotation along screw axis of the helices and the y-axis stands for the depth of the membrane. Color coding was done separately for each helix where blue color represents the low-scoring regions and the red color represents the high-scoring regions. The black bars represent the boundary of the hydrophobic thickness of the implicit membrane model.