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Membrane-binding mechanism of the EEA1 FYVE domain revealed by multi-scale molecular dynamics simulations

Fig 4

Atomistic simulations: distances, H-bonds and stalk tilt angle.

(A) Centre-of-mass distance between the membrane and each of the FYVE heads as function of time. (B) Number of H-bonds with PI(3)P headgroups for the FYVE heads. (C) Angle between the stalk axis and the bilayer normal as a function of time.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1008807.g004