The super repertoire of type IV effectors in the pangenome of Ehrlichia spp. provides insights into host-specificity and pathogenesis
Fig 9
Ankyrin-containing predicted type IV effectors show diverse architectures and inter- and intragenic rearrangements in Ehrlichia spp.
A. Each protein in Ehrlichia spp. pT4E whose architecture includes an ankyrin domain is represented. B. Relative time phylogenetic tree build from 11 nucleotide sequences of Ankyrin-containing predicted type IV effectors (pT4Es). ECH_0653 was used as outgroup. The numbers in front of each node represent the relative theoretical time from the putative common ancestor of two branches. Evolutionary analyses were conducted in MEGA7 [34]. C. Dot plot of regions of similarities between ECH-0684 (x-axis) and ERGA_CDS_03830 (y-axis). This graph was constructed with the dotmatcher software included in the EMBOSS package, where all positions from the first input sequence are compared with all positions from the second input sequence using a specified substitution matrix and using a window size of 50 and a threshold of 50. The two sequences are the axes of the rectangular dotplot. Wherever there is "similarity" between a position from each sequence a dot is plotted.