The super repertoire of type IV effectors in the pangenome of Ehrlichia spp. provides insights into host-specificity and pathogenesis
Fig 8
Protein architecture network of putative effectors for rarely occurring domains.
This network of pT4E protein architectures was drawn using the hive plot algorithm to produce a rational visualization method based only on the network structural properties. Each node represents a specific domain or a list of specific domains (see table) found in Ehrlichia T4Es predicted by S4TE 2.0. Links between domains represents the association between these domains in the architecture of Ehrlichia pT4Es. Nodes representing the most abundant domains presented in Fig 7 (NLS, Coiled-coils, EPIYA and E block domains) and their corresponding links to other nodes are not included in this graph to highlight the less abundant protein domains in Ehrlichia spp predicted T4 effectomes. The table of domains identifies the protein domains for each node (numbered) and their occurrences. All the domains are ranked on the three axes (a1, a2, a3) according to the number of their links. Let X be the number of links between one domain and the others, X < 3 was represented on axis a1, 3 ≥ X ≤ 5 was represented on axis a2, and X > 5 was represented on axis a3.