Biological impact of mutually exclusive exon switching
Fig 5
Examples of MXE events affecting amongst other things.
(A) Protein-protein interaction of the PKM gene. Cancer mutated residues are shown in spacefill. (B) Allosteric regulation of the PFKP gene. Cancer mutated residues are shown in spacefill. (C) Small molecule interaction (PSI) sites in the CRMP gene. We are only showing variable binding zinc/catalytic residues. Zinc molecules are shown green spacefill. (D) Catalytic site residues of gene CG42249 from drosophila. We are only showing variable binding zinc/catalytic residues.