Finding branched pathways in metabolic network via atom group tracking
Fig 2
Branched pathway from pyruvate to L-valine.
a) The known branched pathway from pyruvate to L-valine in KEGG. cr1, cr2 are two sub-branched pathways in this known pathway. b) The found pathway of BPAT-M. c) The found pathway of BPAT-S. d) The found pathway of Retrace. e) The found pathway of BPFinder. dr1, dr2, dr3 are three sub-branched pathways in the found pathway of BPFinder. The compounds circled with dashed ellipses are the branched compounds in the pathways. In the found pathways, the reactions that appear with the same substrates and products in the known pathway are drawn in green. The conserved atom groups from pyruvate in the branched compounds are drawn in red in the dashed rectangles.