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Catalytic promiscuity in the RNA World may have aided the evolution of prebiotic metabolism

Fig 5

Trade-off surfaces with two enzyme activities.

The surfaces delimit the section of the trait space that replicators can occupy in case of A = 2. The surfaces are calculated by Eqs 6 and 7; all replicators take trait values from below the trade-off surfaces shown. The axes are the two enzymatic activities (E1 and E2) and replicability (k). Catalytic (activity/activity) trade-off differs in columns (left: strong, middle: neutral, right: weak) and activity/replicability trade-off differs in rows similarly (bottom: strong, middle: neutral, top: weak).

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1008634.g005