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Catalytic promiscuity in the RNA World may have aided the evolution of prebiotic metabolism

Fig 4

The types of replicators in the two dimensional space of enzymatic activities.

Coloured regions represent parts of the phenotypic trait-space which replicators are permitted to occupy by the trade-off constraints. The concave orange line represents a strong trade-off, while the convex blue line stands for a weak trade-off between enzymatic activities A and B. Specialists (replicators in the green areas) have only one significant enzymatic activity; generalists (red area) feature both activities. Replicators of very weak or no catalytic activity are parasites (black area). While the generalist-specialists continuum is gradual, we distinguish them by artificial boundaries defined by a threshold value m = 0.01 (represented by black lines).

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1008634.g004