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Modeling drug response using network-based personalized treatment prediction (NetPTP) with applications to inflammatory bowel disease

Fig 2

Excerpts from dendrogram shown in S1 Fig.

Clusters of drugs emerge which share similar mechanisms, such as steroids and immunosuppressants (A), topoisomerase blockers used as antibiotics and chemotherapy (B), adrenergic and dopamine receptor drugs (C), and anti-inflammatory and immunomodulating drugs (D). Dendrogram branches are colored by the first level of the anatomic therapeutic chemical classification system (see S1 Fig for legend).

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1008631.g002