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Mitochondrial depolarization promotes calcium alternans: Mechanistic insights from a ventricular myocyte model

Fig 4

Effect of CaMKII activation on the genesis of the Ca2+ alternans.

Bifurcation diagrams of peak values of Ca2+ transients in the last two beats vs. αmPTP for clamped CaMKII activation level 1% (A), 10% (B) and 30% (C), respectively. PCL = 500 ms.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1008624.g004