miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer
Fig 14
Visualizing batch effects in the combined cross-tech miRNA dataset considering the unnormalized data.
(A) Dendrogram with edges colored by dataset. Note that the tree root is outside the displayed axis range. (B) Silhouette plot [67] showing that most samples cluster according to the dataset they originate from. (C) Pairwise Euclidean distances showing a block structure that agrees with the sample dataset of origin.