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miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer

Fig 7

Impact of normalization on the correlation between hsa-miR-29b expression and its in-silico predicted targets according to TargetScan.

(A) AQuN normalized vs Unnormalized (B) miRNA showing normalized is more negatively correlated to the prominent hsa-miR-29b targets in TargetScan as evident in stronger enrichment values.

Fig 7

doi: https://doi.org/10.1371/journal.pcbi.1008608.g007