Conformational plasticity and dynamic interactions of the N-terminal domain of the chemokine receptor CXCR1
Fig 3
Conformational dynamics of the N-terminal region of CXCR1.
Intra-protein contact maps of the N-terminal region of CXCR1 in presence (lower matrix) and absence (upper matrix) of the ligand. Residue-wise contact probabilities of the N-terminal region in apo- and IL8-bound CXCR1 are plotted in the top and bottom diagonal of the matrix, respectively. The amino acid sequence of the N-terminal region is displayed on the top and right. The values of contact probabilities (0.5 nm distance cutoff) are denoted in the color bar. See Methods for more details.