Implications of diffusion and time-varying morphogen gradients for the dynamic positioning and precision of bistable gene expression boundaries
Fig 6
Fronts may localize at multiple points in a domain, resulting in more complicated patterns.
Simulations were performed on the 1D model in S2 Appendix with a = 0.1, D = 0.1 on a 2D reaction domain (bottom) in which the bifurcation parameter α(x) varies only along the horizontal axis (gray dashed line). Top, horizontal cross-sections through the midline show that two opposing fronts appear and propagate toward the nearest localization point, resulting in refinement of a stripe pattern from either direction over time.