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Four different mechanisms for switching cell polarity

Fig 8

Stochastic switching.

A Power spectral density of A1(t)−A2(t) in the absence of any X signal for different noise strengths. A peak in the power spectrum at high noise indicates stochastic coherence. B The maximal power density relative to the power at zero frequency shows a non-monotonic dependence on the noise strength. C The mean time between switching events, defined as points when A1 = A2, varies as different signals are applied, at a noise level N = 103.75. Signals that generate deterministic oscillations have been excluded. Times between switches were extracted from stochastic trajectories with the signal applied continuously for 50000 min.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1008587.g008