Voxelized simulation of cerebral oxygen perfusion elucidates hypoxia in aged mouse cortex
Fig 2
Illustration of the masking algorithm for labeling at different resolutions in the cortical microdomain.
A) The cortical network (E1.1) is labeled by pressure visualizing arteries (red), veins (blue) and connecting capillaries. B-C) This cortical network has been labeled a mesh visualized at many resolutions. Coloration of mesh is tri-color; red = blood, grey = endothelial, and blue = extravascular cells. Note, most of the cells belong to the extravascular space (blue). The blood lumen is marked by intravascular elements (red). Mass transfer occurs at the interface elements (grey). D-F) Visualization of mesh labeling at three resolutions reflects the capability of the labeling to resolve the connectivity between vasculature and tissue at all length scales. F) The distribution of endothelial layer, intravascular, and extravascular elements can be seen at the finest resolution.