A multiscale model via single-cell transcriptomics reveals robust patterning mechanisms during early mammalian embryo development
Fig 3
Sensitivity of selective adhesion starting time.
(a) Ratio of Nanog+/Gata6+/DP/DN at 128-cell stage for different selective adhesion (SA) starting time; (b) Success rate for embryo development at 128-cell stage for different SA starting time. (c) Spatial pattern of simulation where selective adhesion starts from 128-cell stage (a partially successful case) and simulation where selective adhesion starts from 64-cell stage (a successful case).