Zika virus dynamics: Effects of inoculum dose, the innate immune response and viral interference
Table 1
Estimated population parameters from fitting the indicated models to viral load data from all animals using a non-linear mixed effects model.
An explicit covariate relationship between inoculum dose and initial viral load V0 is incorporated, with the median population estimate for log10 V0 at each inoculum dose shown in italics. Relative standard errors are shown in parentheses. Fixed parameters used in the model fits are: k = 8 d-1, c = 10 d-1, s = 1 d-1, α = 2 d-1, K = 103, n = 0.25, T(0) = 105 ml-1, each with no variability.