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PremPS: Predicting the impact of missense mutations on protein stability

Table 4

Pearson correlation coefficient between experimental and predicted ΔΔG values calculated using experimental and modeled structures in different ranges of sequence identity.

Selected models: when several templates were available in a given range of sequence identity, the one whose sequence identity with the target was closest to the middle of the range and deviation from the experimental structure was the lowest was selected. Leave-one-protein-out validation (CV4) results are shown for S2297 and RS2297. More details are provided in S13 Table.

Table 4

doi: https://doi.org/10.1371/journal.pcbi.1008543.t004