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Systems biology predicts that fibrosis in tuberculous granulomas may arise through macrophage-to-myofibroblast transformation

Fig 1

Schematic diagram of the two main organizational types of granuloma-associated fibrosis in TB granulomas indicating the two main types of fibrosis observed in NHP granulomas.

Yellow cells represent myofibroblasts, green represent macrophages, and grey fibroblasts.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1008520.g001