Multi-scale modeling of macrophage—T cell interactions within the tumor microenvironment
Fig 12
Cycling macrophage depletion with increased tumor proliferation and macrophage recruitment rates.
The macrophage recruitment rate is doubled, and tumor proliferation rate increased to 1.2/day. (A) fraction of tumors removed after starting simulation, (B) average time needed to remove the tumor, (C) the maximum number of M1 macrophages, (D) the maximum number of total T cells, (E) the maximum number of active T cells.