Multi-scale modeling of macrophage—T cell interactions within the tumor microenvironment
Fig 10
Time courses with increased tumor proliferation and macrophage recruitment rates, without treatment.
The macrophage recruitment rate is doubled, and tumor proliferation rate increased to 1.2/day. Time courses for tumors that were not removed by the immune system are shown in black; those for tumors that were removed are shown in red. (A) Cancer cells, (B) M0 cells, (C) M1 cells, (D) M2 cells, (E) Total T cells, (F) Active T cells, (G) Average IL-4, (H) Maximum IL-4, (I) Average IFN-γ, (J) Maximum IFN-γ.