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Multi-scale modeling of macrophage—T cell interactions within the tumor microenvironment

Fig 2

Time courses with baseline parameters and no treatment.

Time courses for tumors that were not removed by the immune system are shown in black; those for tumors that were removed are shown in red. There is only one simulation here that led to tumor removal. (A) Cancer cells, (B) M0 cells, (C) M1 cells, (D) M2 cells, (E) total T cells, (F) active T cells, (G) average IL-4, (H) maximum IL-4, (I) average IFN-γ, (J) Maximum IFN-γ. (G)–(J): units are number of molecules.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1008519.g002