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Modeling the circadian regulation of the immune system: Sexually dimorphic effects of shift work

Fig 3

Predicted clock gene time profiles.

Comparison of predicted time profiles (solid lines) for Per, Cry, Rev-Erb, Ror and Bmal1, with experimental data (circles) for Per2, Cry1, Rev-Erbα, Rorc, and Bmal1 mRNA expression levels obtained in mouse lungs in constant darkness. Gray shading and white regions correspond to activity and restcycles, respectively.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1008514.g003