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PIEZO1 and the mechanism of the long circulatory longevity of human red blood cells

Fig 2

Testing the quantal hypothesis; predicted changes in Relative Cell Volumes at different PzCa levels.

The trends shown only for the first thirty days remained unchanged for 120 days. Pump decay rate constants were set to zero. Triangles: effects of increasing JS turnover rate five-fold at PzCa = 70/h. Note that even at the highest PzCa shown, final dehydration does not exceed 10% of initial RCV.

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1008496.g002