Context-specific network modeling identifies new crosstalk in β-adrenergic cardiac hypertrophy
Fig 8
Revised model of β-adrenergic cardiac hypertrophy.
The solid red arrows exhibit predicted and validated interactions in ISO-specific context. The dashed red arrows illustrate proposed interactions predicted by model based on the new experimental data on the effects of CaMKII inhibition on ISO-induced ERK1/2 activity.