Bursting in cerebellar stellate cells induced by pharmacological agents: Non-sequential spike adding
Fig 13
Pseudo-plateau bursting in the CSC model defined by the full system (1).
A) Time course of the membrane voltage V when gK = 12 μS.cm−2, gK(Ca) = 7 μS.cm−2 and gHVA = 0.22 μS.cm−2. B) Bifurcation diagram of the fast subsystem, represented by the variable V, with respect to hA using the same values of maximum conductances listed in A. As in Fig 10, the stable (unstable) branches of equilibria are plotted as solid (dotted) lines, while envelopes of unstable periodic orbits are plotted as green dotted lines. Notice the absence of the isola near SN1 seen in Fig 10. C) The BPO shown in panel A superimposed on the critical manifold of system (1) shown as a gray surface in the (hA, Ca, V)-space. The family of envelopes of unstable periodic orbits emanating from the curve of Hopf bifurcations lying on the upper sheet of the critical manifold is shown as a green surface. D) Two-parameter continuation of the bifurcation points SN1, SN2, HB and HC detected in panel B plotted in the (hA, Ca)-space along with one pseudo-plateau bursting cycle (blue); the flow direction is indicated with the arrows and active and silent phases are shaded dark and light blue, respectively. The bifurcation curves are color-coded according to the legend.