A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness
Fig 6
Sensitivity analysis of the number of infected epithelial cells vs time for variations in virus-receptor association affinity kon and immune response delay coefficient βdelay, showing regions with distinct infection dynamics.
Same parameter sweep as Fig 5. The number of infected epithelial cells for each simulation replica for each parameter set, plotted on a logarithmic scale, vs time displayed in minutes. See Fig 4 for the definitions of the classes of infection dynamics.