Identifying the drivers of multidrug-resistant Klebsiella pneumoniae at a European level
Fig 1
The workflow of the modeling approach.
Consumption and resistance data were acquired from ECDC, and other parameters were found in the literature or used as free parameters. The model was fit to the data reported by ECDC to optimize the free parameters. Sensitivity analyses were performed to test the robustness of the model. Counterfactual scenarios were applied to understand the functional dependencies of the prevalence of resistance from possible drivers.