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Within-host mechanisms of immune regulation explain the contrasting dynamics of two helminth species in both single and dual infections

Fig 2

Single infection simulations (blue) and observation data (black).

Mean intensity of infection (A and D), specific IgA response estimated using adult worms as a source of antigen (B and E), and IL4 expression (C and F) over the course of the infection. Observed data (geometric mean multiplied/divided by the S.D. error factor (circle)) and estimated values (star) with the relative 90% confidence interval (shade) are reported for both T. retortaeformis (A-C) and G. strigosum (D-F).

Fig 2

doi: https://doi.org/10.1371/journal.pcbi.1008438.g002