Differential effects of propofol and ketamine on critical brain dynamics
Fig 10
Differences in multi-scale complexity between conditions.
Integration of information across scales for awake (purple) vs. ketamine (grey) (A, B) and awake vs. propofol (orange) (C, D). Complexity was calculated using the NCC Toolbox [48], using the measure first proposed by Tononi, Sporns & Edelman [41]. While the ketamine condition (grey) was associated with a noticable decrease in complexity compared the awake condition (purple), it was a much smaller decrease than what was observed in the propofol condition, which was an order of magnitude less complex. Note that the total value of complexity is not the greatest value, but rather, the difference between the area under the curves for the linear fit and the true non-linear integration.