Probabilistic transmission models incorporating sequencing data for healthcare-associated Clostridioides difficile outperform heuristic rules and identify strain-specific differences in transmission
Fig 5
Proportion of cases acquired from each transmission route, by sequence type.
Panels A to C show the estimated proportion of cases acquired from each of the 3 major source types, known patients (A, blue), hospital background sources (B, green) and the community (C, gold). Panels D to F subdivide the cases shown in panel A, into those acquired by direct ward contact (D), ward-based spores (E) and hospital-wide transmission (F). Note the y-axis scale differs between the upper panels and lower panels, to allow for comparison of the relative contribution of ward, spore and hospital-wide routes to transmission from other cases, and hospital vs. community for background transmission.