Probabilistic transmission models incorporating sequencing data for healthcare-associated Clostridioides difficile outperform heuristic rules and identify strain-specific differences in transmission
Fig 3
Source type and individual source attribution in simulated data.
The left-hand columns (panels A and C) display the accuracy of inferences about the source type, i.e. distinguishing between hospital background, community background, ward, spore and hospital-wide transmission. The right-hand columns (panels B and D) display the accuracy of inferences about the specific patient source of each infection (for background source types this is an unknown source). Panels A and B display inferences from the full transmission model. Panels C and D display the accuracy of predictions running an inference model without using genetic data (circles) or based on a heuristic rule (squares). CI, credibility interval.