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Spatial considerations in the resolution of inflammation: Elucidating leukocyte interactions via an experimentally-calibrated agent-based model

Fig 12

Percentage change in the maximal level of pro-inflammatory mediator c at t = 5000 on varying each individual parameter by + 50% (green) and −50% (red), from the baseline parameter values given in Table 1, with healthy choices of chemotaxis parameters (kgrad = 80, σmem = 1).

Triangles denote the mean percentage change in the response; error bars denote plus/minus one standard deviation. (For probabilities for which an increase of 50% results in a choice greater than one, the green results correspond to simulations with unit probability.) Note that a change in response of −100% corresponds to a switch from a chronic to a healthy outcome.

Fig 12

doi: https://doi.org/10.1371/journal.pcbi.1008413.g012