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Tracking collective cell motion by topological data analysis

Fig 13

Simulation of the antagonistic migration assay: One population advances pushing back the other, while the interfaces mix, creating scattered islands of cells of different type.

Parameters and times are as in Fig 12, except that one fifth of the overall population (randomly placed green and magenta cells) have Λ12 = −7.5 (population mixing) and the other four fifths have Λ12 = −6.0 (population segregation). The marked region has similar size to that reported in experiments [27] and will be used in our TDA studies. See S5 Video.

Fig 13

doi: https://doi.org/10.1371/journal.pcbi.1008407.g013