Inferring evolutionary pathways and directed genotype networks of foodborne pathogens
Fig 5
The structure of the centrality-prevalence space, revealed by the expected values of both successful and unsuccessful evolutionary paths.
For every MLVA profile, the point size is shown in proportion to the average change in prevalence: positive change is shown with red colour, and negative change with blue. Intensity of each colour indicates the estimated probability density, given the average changes in prevalence for either positive or negative profiles. Similar to Fig 4, the transition region (intense red colour) is shaped by the successful profiles with high centrality and medium cluster prevalence. The evolutionary paths originating from profiles in this region tend to develop from right to left and from bottom to top, producing the higher average change in prevalence. Conversely, the bottleneck region (intense blue colour) is formed by unsuccessful profiles with the centrality around 0.03 and the cluster prevalence just below 102. The evolutionary paths originating from these profiles tend to follow the opposite direction: from left to right and from top to bottom, reducing their prevalence on average.