Active probing to highlight approaching transitions to ictal states in coupled neural mass models
Fig 3
Feature series and probing efficiency for model setting I-A.
For population 1, excitability increase is correlated with variance even with passive observation. However, increased amplitude probing responses from population 2 reflect gradual changes of A1 towards ictogenesis. (a) shows a simplified illustration of the model setting. For (b) variance, (c) skewness, (d) kurtosis and (e) lag-1 AC features, top rows show feature values extracted from the output of each population, as the excitability gain parameter (A1) is increased. (f) shows the inter-population synchronization as measured by the mutual information feature. Bottom row shows Spearman’s rank correlation between each feature series and the shifted parameter (A1), as stimulus amplitude is increased. Black dots indicate significant differences from passive observation (stim. Amplitude = 0) according to Tukey’s HSD.