Active probing to highlight approaching transitions to ictal states in coupled neural mass models
Fig 2
Neuronal mass model outputs with and without active probing stimuli.
Simulation changing parameter A1 from 4.30 to 4.95 (B = 40, G = 20) to elicit ictal activity in the end, with (a) passive observation or (b) active probing of both populations. Outputs are shown for population 1 (a.1 and b.1) and population 2 (a.2 and b.2), with tick marks showing stimuli onsets for (b). Ictal-like activity in the form of sustained discharges of spikes is observed for population 1 at the end of both simulations. ILS appear before this transition and are elicited even further in advance by stimulation. (c) Bottom plots show overlapped and mean response waveforms for increasing values of A1 for (c.1) population 1 and (c.2) population 2. Gradual response changes are observed until the appearance of ILS for A1 = 4.5 and ictal activity at A1 = 5.0.