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Comparing mutational pathways to lopinavir resistance in HIV-1 subtypes B versus C

Fig 5

Empirical null distribution of pairwise Jaccard distances estimated by permuting group labels.

Displayed are the histograms of Jaccard distances for the comparison of subtypes B and C for H-CBN2 posets with A 11 mutations and B 18 mutations, as well as the histograms of Jaccard distances for the comparison of two data sets for subtype C for H-CBN2 posets with C 11 mutations and D 19 mutations. Vertical dotted lines indicate the distance between the CBNs obtained from the observed data.

Fig 5

doi: https://doi.org/10.1371/journal.pcbi.1008363.g005