Leveraging functional annotation to identify genes associated with complex diseases
Fig 6
Regional Manhattan plot around TMEM135.
The listed SNP (rs541458) is one of the identifed eQTLs by T-GEN in the imputation model of TMEM135. Among all eQTL of TMEM135 identified by T-GEN, this SNP also has the strongest GWAS signal in the published AD GWAS study.