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Leveraging functional annotation to identify genes associated with complex diseases

Fig 3

More genes were identified as trait-associated by T-GEN across 207 traits from the LD Hub.

Applied to 207 traits from LD Hub, significant trait-associated genes were identified in 26 tissues (p-values threshold: 0.05 divided by the number of gene-tissue pairs). Each boxplot represents the distribution of the number of differences between that identified from our tissue-specific analysis and that identified from the four other methods.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1008315.g003