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Increased comparability between RNA-Seq and microarray data by utilization of gene sets

Fig 3

Top; two scatterplots of samples from the CCLE datasets, after log2 transformation, that show concordance between raw gene expression levels as determined by microarray and RNA-Seq. Spearman correlation coefficients are given for each plot. The clear horizontal lines near the bottom are an artifact of the nature of RNA-Seq data which are integer counts in contrast to the analog microarray values. Bottom; the first two principal components showing the distribution of samples for each dataset. Coloring of the samples is histology based and the crosshairs denote the two samples used for the scatterplots in the top figure.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1008295.g003