Models of SIV rebound after treatment interruption that involve multiple reactivation events
Fig 2
Comparison between the approximation for the time-to-rebound distribution and simulated rebound times.
The simulated empirical distributions are shown in color, and our approximation is shown in black. (A) The probability density function (PDF; defined by Eq 6). (B) The survival function (i.e. the fraction of subjects S(t) that do not have a detectable VL at time t). For the top, middle, and bottom panels different values of λ are used (λ = 5 d−1, 1 d−1, and 0.2 d−1 respectively). Notice the different time scale on the horizontal axes. For the remaining parameters, we used the values: g = 0.5 d−1, v0 = 0.1 copies mL−1, LoD ℓ = 50 copies mL−1.