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Graph-theoretical formulation of the generalized epitope-based vaccine design problem

Fig 1

Epitope-based vaccine pipeline.

An epitope-based vaccine pipeline is comprised of three major steps: (1) epitope discovery, (2) selection, and (3) assembly. Different types of vaccine design exist: (3a) epitope mixture, (3b) string-of-beads, and (3c) mosaics.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1008237.g001