Mathematical model predicts response to chemotherapy in advanced non-resectable non-small cell lung cancer patients treated with platinum-based doublet
Fig 4
Long-term response to palliative platinum-doublet chemotherapy as a function of initial response.
A) Initial response (R; log-transformed tumor reduction after treatment) versus long-term response (OS; overall survival in months) to platinum doublet chemotherapy in virtual cohort. Patients are divided into four groups CR (complete response), PR (partial response), SD (stable disease) and PD (progressive disease), based on the initial response to treatment (see Table 1). B) Overall survival as a function of initial response to platinum doublet chemotherapy in the clinical cohort.