Causal network inference from gene transcriptional time-series response to glucocorticoids
Fig 6
Validation of inferred network on overexpression data.
A-B) Regression of one-hot encoding of positive (negative for B) edges as the predictor against the VAR model edge coefficient from the overexpression data as the response. A 1 indicates that an edge had a positive (in A) or negative (in B) coefficient in the original inferred network (FDR ≤ 0.2). C) For the 123 causal edges from TFCP2L1, regression of edge sign as the predictor against the VAR model edge coefficient from TFCP2L1 overexpression data as the response.