Causal network inference from gene transcriptional time-series response to glucocorticoids
Fig 4
Conditional Granger causality reveals opposite sign of relationship KRT6A → NKAIN4.
A) Time series and B) scatter plot of expression values from KRT6A and NKAIN4. C) Time series and D) scatter plot of expression values from KRT6A and residual expression values from NKAIN4 after controlling for the effects of other covariates in NKAIN4. Each y-axis tick in A and C indicates 0.1 unit-variance standardized ln(TPM), where TPM is Transcripts Per kilobase Million. The grey line marks zero-centered expression. B and D axes are in units of ln(TPM).