A greedy classifier optimization strategy to assess ion channel blocking activity and pro-arrhythmia in hiPSC-cardiomyocytes

Fig 3

Section Heterogeneity: Finite element meshes of MEA used and example of heterogeneity field.

Left: Finite element mesh representing one well including 9 electrodes of the 6–well MEA device from Multichannel Systems (used in TdP classification). MEA device documentation is available on: http://www.qichi-instruments.com/bookpic/20163120452599.pdf. Right: Finite element mesh representing one well including 8 electrodes of the 96–well MEA device from Axion Biosystems with an example of generated cell heterogneity field (used in Channel classification). MEA device documentation is available on: https://www.axionbiosystems.com/sites/default/files/resources/mea_plates-brochure-rev_06.pdf.